Mariana Malvicini Selected Research

Hymecromone

1/2022	Glycosylated 4-methylumbelliferone as a targeted therapy for hepatocellular carcinoma.
12/2018	4Mu Decreases CD47 Expression on Hepatic Cancer Stem Cells and Primes a Potent Antitumor T Cell Response Induced by Interleukin-12.
9/2015	Tumor Microenvironment Remodeling by 4-Methylumbelliferone Boosts the Antitumor Effect of Combined Immunotherapy in Murine Colorectal Carcinoma.
8/2015	4-methylumbelliferone inhibits hepatocellular carcinoma growth by decreasing IL-6 production and angiogenesis.
3/2012	Antitumor effects of hyaluronic acid inhibitor 4-methylumbelliferone in an orthotopic hepatocellular carcinoma model in mice.

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Mariana Malvicini Research Topics

Disease

20	Neoplasms (Cancer) 01/2022 - 03/2009
10	Hepatocellular Carcinoma (Hepatoma) 01/2022 - 03/2012
8	Colorectal Neoplasms (Colorectal Cancer) 01/2018 - 06/2009
7	Liver Cirrhosis (Hepatic Cirrhosis) 01/2021 - 05/2011
5	Fibrosis (Cirrhosis) 11/2016 - 03/2012
4	Carcinoma (Carcinomatosis) 01/2015 - 06/2011
1	Neoplasm Metastasis (Metastasis) 01/2021
1	Wounds and Injuries (Trauma) 06/2019
1	Liver Neoplasms (Liver Cancer) 12/2018
1	Precancerous Conditions 08/2015

Drug/Important Bio-Agent (IBA)

6	Hyaluronic Acid (Hyaluronan)IBA 12/2018 - 06/2009
6	Interleukin-12 (IL 12)IBA 12/2018 - 12/2009
5	HymecromoneIBA 01/2022 - 03/2012
5	Thioacetamide (Thioacetamid)IBA 01/2020 - 03/2015
5	Cyclophosphamide (Cytoxan)FDA LinkGeneric 09/2015 - 12/2009
2	Therapeutic UsesIBA 01/2021 - 01/2015
2	Insulin (Novolin)FDA Link 01/2020 - 03/2015
2	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2020 - 03/2015
2	Insulin-Like Growth Factor I (IGF-1)IBA 01/2020 - 03/2015
2	Messenger RNA (mRNA)IBA 12/2018 - 08/2015
2	Interleukin-8 (Interleukin 8)IBA 10/2017 - 01/2014
2	Proteins (Proteins, Gene)FDA Link 08/2015 - 06/2010
1	Pharmaceutical PreparationsIBA 01/2022
1	GTP Phosphohydrolases (GTPases)IBA 01/2021
1	1D-142IBA 01/2021
1	GalactosamineIBA 06/2019
1	Concanavalin AIBA 06/2019
1	JIB-04IBA 01/2019
1	Lysine (L-Lysine)FDA Link 01/2019
1	MethyltransferasesIBA 01/2019
1	EnzymesIBA 01/2019
1	Histone Acetyltransferases (Histone Acetyltransferase)IBA 01/2019
1	Epithelial Cell Adhesion MoleculeIBA 12/2018
1	Monoclonal AntibodiesIBA 01/2018
1	NivolumabIBA 01/2018
1	CytokinesIBA 10/2017
1	Biological ProductsIBA 10/2017
1	Interleukin-6 (Interleukin 6)IBA 08/2015
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 08/2015
1	Hypoxia-Inducible Factor 1IBA 01/2015
1	VaccinesIBA 01/2014
1	Glucose-6-Phosphate Isomerase (Phosphoglucose Isomerase)IBA 01/2014
1	Autocrine Motility Factor ReceptorsIBA 01/2014
1	CollagenIBA 01/2013
1	Antineoplastic Agents (Antineoplastics)IBA 03/2012
1	Conditioned Culture MediaIBA 10/2011
1	Becaplermin (PDGF-BB)FDA Link 05/2011
1	Glycoproteins (Glycoprotein)IBA 06/2010
1	Cysteine (L-Cysteine)FDA Link 06/2010

Therapy/Procedure

9	Therapeutics 01/2022 - 12/2009
6	Immunotherapy 09/2020 - 03/2009
3	Ligation 06/2019 - 01/2013
1	Drug Therapy (Chemotherapy) 01/2015
1	Radiotherapy 01/2015
1	Molecular Targeted Therapy 01/2015